ITP Thesis Ideas - Application Prototyping

I've been considering ITP thesis ideas (see also "Social Tech Under the Radar"), and I keep coming back to the idea of prototyping. Based on my work with BeeMe and at Etsy, I've seen the value of using prototypes for product discovery and refinement. I'd like to experiment with and improve upon existing approaches: agile development, rapid prototyping techniques, development frameworks like Ruby on Rails, third-party customer support/feedback tools like getsatisfaction and uservoice, and remote user testing services like I may use a mobile application like BeeMe or EtsyLocal as a case study.

Right now the goal is to narrow the scope of my ideas into something I can accomplish over the next few months. Not a lot of time!